Doç. Dr. Ayşe KARATUĞ KAÇAR

Yayın Ağı

SCI, SSCI ve AHCI İndekslerine Giren Dergilerde Yayınlanan Makaleler

Studies on Treatment Within the Scope of Medical Biotechnology for Pancreatic Diseases

Aylar D., Karatuğ Kaçar A.

Molecular Biotechnology , cilt.67, sa.4, ss.1321-1335, 2025 (SCI-Expanded) Sürdürülebilir Kalkınma

Glucotoxicity suppresses function of pancreatic beta and duct cells via miR-335-targeted Runx2 and insulin-mediated mechanism

OKTAYOĞLU S., SANCAR S., Karatug-Kacar A., BOLKENT Ş.

PROTOPLASMA , cilt.262, sa.2, ss.341-352, 2025 (SCI-Expanded) Sürdürülebilir Kalkınma

Characterization and comparison of insulinoma tumor model and pancreatic damage caused by the tumor, and identification of possible markers

Karatuğ Kaçar A., Bulutay P., Aylar D., Celikten M., Bolkent Ş.

MOLECULAR BIOLOGY REPORTS , cilt.51, sa.1, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

The therapeutic effects of exosomes the first time isolated from pancreatic islet-derived progenitor cells in the treatment of pancreatic cancer

Hasoglu I., KARATUĞ KAÇAR A.

PROTOPLASMA , cilt.261, sa.2, ss.281-291, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

Exploring dual effects of dinutuximab beta on cell death and proliferation of insulinoma

KARATUĞ KAÇAR A.

CHEMICAL BIOLOGY & DRUG DESIGN , cilt.103, sa.1, 2024 (SCI-Expanded) Sürdürülebilir Kalkınma

BuOH fraction of Salix Babylonica L. extract increases pancreatic beta-cell tumor death at lower doses without harming their function

KARATUĞ KAÇAR A., Aylar D., Kazdal F., BAHADORI F.

TOXICOLOGY IN VITRO , cilt.90, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

Epibrassinolide impaired colon tumor progression and induced autophagy in SCID mouse xenograft model via acting on cell cycle progression without affecting endoplasmic reticulum stress observed in vitro

YERLİKAYA P. O., Adacan K., KARATUĞ KAÇAR A., ÇOKER GÜRKAN A., Arisan E. D.

INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY , cilt.155, 2023 (SCI-Expanded) Sürdürülebilir Kalkınma

miR-375 induces adipogenesis through targeting Erk1 in pancreatic duct cells under the influence of sodium palmitate.

Gezginci-Oktayoglu S., Sancar S., Karatug-Kacar A., Bolkent S.

Journal of cellular physiology , cilt.236, ss.3881-3895, 2021 (SCI-Expanded) Sürdürülebilir Kalkınma

Investigation of cell death mechanism and activity of esculetin-loaded PLGA nanoparticles on insulinoma cells in vitro.

Karatug Kacar A., Bahadori F., Tekkeli Ş. E., Topçu G., Bolkent S.

The Journal of pharmacy and pharmacology , cilt.72, ss.592-606, 2020 (SCI-Expanded) Sürdürülebilir Kalkınma

The effects of atorvastatin on the kidney injury in mice with pulmonary fibrosis.

Karatug Kacar A., Yildirim M., Bolkent Ş., Oztay F.

The Journal of pharmacy and pharmacology , cilt.71, ss.1301-1310, 2019 (SCI-Expanded)

Vitronectin, fibronectin and epidermal growth factor induce proliferation via the JNK and ERK pathways in insulinoma INS-1 cells.

Karatug Kacar A., Bolkent Ş.

Cytotechnology , cilt.71, ss.209-217, 2019 (SCI-Expanded)

4-Methylcatechol stimulates apoptosis and reduces insulin secretion by decreasing betacellulin and inhibin beta-A in INS-1 beta-cells.

Karatug Kacar A., Gezginci-Oktayoglu S., Bolkent Ş.

Human & experimental toxicology , cilt.37, sa.11, ss.1123-1130, 2018 (SCI-Expanded)

Involvement of dying beta cell originated messenger molecules in differentiation of pancreatic mesenchymal stem cells under glucotoxic and glucolipotoxic conditions.

Gezginci-Oktayoglu S., Onay-Ucar E., Sancar-Bas S., Karatug-Kacar A., Arda E. Ş. N., Bolkent Ş.

Journal of cellular physiology , cilt.233, sa.5, ss.4235-4244, 2018 (SCI-Expanded) Sürdürülebilir Kalkınma

Necrotic cell death occur via JNK pathway with the activity of transcription factor c-Jun by 4-MC in INS-1 cell line.

Karatug Kacar A., Bolkent Ş.

Journal of cellular biochemistry , cilt.119, ss.2048-2060, 2018 (SCI-Expanded)

Carbon tetrachloride-induced kidney damage and protective effect of Amaranthus lividus L. in rats

Yilmaz-Ozden T., Can A., Karatug A., Pala-Kara Z., Okyar A., Bolkent S.

TOXICOLOGY AND INDUSTRIAL HEALTH , cilt.32, sa.6, ss.1143-1152, 2016 (SCI-Expanded)

Nerve Growth Factor Neutralization Suppresses beta-Cell Proliferation Through Activin A and Betacellulin

Gezginci-Oktayoglu S., Karatug A., Bolkent S.

PANCREAS , cilt.44, sa.2, ss.243-249, 2015 (SCI-Expanded)

Regulation of oxidative stress and somatostatin, cholecystokinin, apelin gene expressions by ghrelin in stomach of newborn diabetic rats.

Coskun Z. M., Sacan O., Karatug A., Turk N., Yanardag R., Bolkent S., et al.

Acta histochemica , cilt.115, sa.7, ss.740-7, 2013 (SCI-Expanded) Sürdürülebilir Kalkınma

The potential role of combined antioxidant treatment on pancreas of STZ-diabetic mice

Karatug A., Bolkent S.

EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY , cilt.65, ss.255-262, 2013 (SCI-Expanded) Sürdürülebilir Kalkınma

Acute effects of methiocarb on oxidative damage and the protective effects of vitamin E and taurine in the liver and kidney of Wistar rats

Ozden S., Catalgol B., Gezginci-Oktayoglu S., Karatug A., Bolkent S., Alpertunga B.

TOXICOLOGY AND INDUSTRIAL HEALTH , cilt.29, sa.1, ss.60-71, 2013 (SCI-Expanded)

Alterations in kidney tissue following zinc supplementation to STZ-induced diabetic rats

Karatug A., Kaptan E., Bolkent Ş., Mutlu O., Yanardag R.

Journal of Trace Elements in Medicine and Biology , cilt.27, sa.1, ss.52-57, 2013 (SCI-Expanded) Sürdürülebilir Kalkınma

The relation among NGF, EGF and insulin is important for triggering pancreatic beta cell apoptosis

Gezginci-Oktayoglu S., Karatug A., Bolkent S.

DIABETES-METABOLISM RESEARCH AND REVIEWS , cilt.28, sa.8, ss.654-662, 2012 (SCI-Expanded)

Regulation of gene expression and biochemical changes in small intestine of newborn diabetic rats by exogenous ghrelin

Karatug A., Sacan O., Coskun Z. M., Bolkent S., Yanardag R., Turk N., et al.

PEPTIDES , cilt.33, sa.1, ss.101-108, 2012 (SCI-Expanded) Sürdürülebilir Kalkınma

Exendin-4 improves hepatocyte injury by decreasing proliferation through blocking NGF/TrkA in diabetic mice

Gezginci-Oktayoglu S., Sacan O., Yanardag R., Karatug A., Bolkent S.

PEPTIDES , cilt.32, sa.2, ss.223-231, 2011 (SCI-Expanded) Sürdürülebilir Kalkınma

Diğer Dergilerde Yayınlanan Makaleler

The combined ameliorative effects of α-lipoic acid, selenium, and vitamin E on the livers of STZ-diabetic mice

Karatuğ Kaçar A., Ertik O., Coşkun Yazıcı Z. M., Bolkent H. S., Yanardağ R., Bolkent Ş.

Istanbul Journal of Pharmacy , cilt.53, sa.2, ss.199-210, 2023 (Hakemli Dergi) Sürdürülebilir Kalkınma

The Reason for the Size Differences of the Isolated Exosomes and the Importance of these Differences

Hasoğlu I., Karatuğ Kaçar A.

International Journal of Diabetes & Metabolic Disorders , cilt.8, sa.2, ss.322-324, 2023 (Hakemli Dergi)

Damage to Liver Tissue Caused by Valproic Acid Used for Treating Epilepsy: Protective Effects of Vitamin B6

Türkyılmaz İ. B., Karatuğ Kaçar A., Bolkent S., Yanardag R.

Archives of epilepsy (Online) , cilt.29, sa.1, ss.9-15, 2023 (Hakemli Dergi)

Dinutuximab beta-targeted therapy kills beta-cell tumors of the pancreas

KARATUĞ KAÇAR A., ADIGÜZEL Z.

Holistic Integrative Oncology Springer Science and Business Media LLC , cilt.2, ss.1-9, 2023 (Hakemli Dergi)

The Effects of Ghrelin on Renal Complications in Newborn Diabetic Rats

Karatuğ Kaçar A., Saçan Ö., Öziçli N., Bolkent Ş., Yanardağ R., Bolkent H. S.

European Journal of Biology , cilt.79, sa.1, ss.1-6, 2020 (Hakemli Dergi) Sürdürülebilir Kalkınma

Effects of boric-acid-applied green tea on the expressions of heat shock proteins in MCF-7 cells

Ersöz M., Karatug Kacar A., Sezekler I., Coskun Z. M.

CUKUROVA MEDICAL JOURNAL , cilt.44, ss.66-71, 2019 (ESCI)

The Effects of Camellia sinensis Extract on Proliferation, Apoptosis and Oxidative Stress in Insulinoma INS-1 Cells

Karatuğ Kaçar A., Ersöz M., Sezekler I., Coskun Z. M.

Bezmialem Science , cilt.7, sa.2, ss.80-85, 2018 (Hakemli Dergi)

Effects of taurine and vitamin E on lipid peroxidation, antioxidant system and histological changes in Wistar rat liver and kidney after short-term exposure of methiocarb.

Özden S., BOLKENT Ş., GEZGİNCİ OKTAYOĞLU S., Arda Pirincci P., KARATUĞ A., ALPERTUNGA B.

Journal of Faculty of Pharmacy of Istanbul University , cilt.42, sa.2, ss.83-102, 2012 (Hakemli Dergi)

The effect of vitamin B6 on the liver of diabetic rats: A morphological and biochemical study

Bolkent S., Karatug A., Sacan O., YANARDAĞ R.

IUFS JOURNAL OF BİOLOGY , cilt.67, sa.1, ss.1-7, 2008 (Hakemli Dergi) Sürdürülebilir Kalkınma

Hakemli Bilimsel Toplantılarda Yayımlanmış Bildiriler

Proteomıc Investıgatıon Of The Effects Of Dınutuxımab Beta In Insulınoma Ins-1 Cells.

KARATUĞ KAÇAR A.

Uluslararası Biyokimya Kongresi 2023 // 34. Ulusal Biyokimya Kongresi, Muğla, Türkiye, 29 Ekim - 01 Kasım 2023, (Özet Bildiri)

Insulinoma INS-1 cells undergo both cell death and cell proliferation with Dinutuximab beta treatment under different conditions.

Karatuğ Kaçar A.

6th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2023), Ankara, Türkiye, 11 - 13 Ekim 2023, ss.12, (Özet Bildiri)

Administration of dinutuximab beta to insulinoma INS-1 cells under cytotoxic conditions causes cell dysfunction and increases insulin secretion by increasing Ca2+ levels and reducing K+ channel proteins.

Karatuğ Kaçar A.

8th World Congress of Oxidative Stress, Calcium Signaling and TRP Channels, Isparta, Türkiye, 5 - 08 Eylül 2023, ss.2, (Özet Bildiri)

Dual-targeted and biocompatible nanoparticles loaded with esculetin and curcumin cause the death of pancreatic cancer cells

Nurdogan A. N., Sak R., Ergin Kızılçay G., Bahadorı F., Karatuğ Kaçar A.

17th INTERNATIONAL NANOSCIENCE & NANOTECHNOLOGY CONFERENCE, İzmir, Türkiye, 27 - 29 Ağustos 2023, ss.117, (Özet Bildiri)

THE COMBINED EFFECTS OF α-LIPOIC ACID, VITAMIN E AND SELENIUM ON KIDNEY TISSUE OF STZ-DIABETIC MICE

ERTİK O., KARATUĞ KAÇAR A., BOLKENT Ş., YANARDAĞ R.

7th ASIA PACIFIC International Modern Sciences Congress, Endonezya, 4 Kasım - 05 Aralık 2022, (Özet Bildiri) Sürdürülebilir Kalkınma

Exosome isolation and characterization from PID-PC, INS-1, and MiaPaca-2 cells and investigation of the effect of isolated exosomes from PID-PC on pancreatic cancer

Hasoğlu İ., Karatuğ Kaçar A.

5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022), Ankara, Türkiye, 23 Kasım 2022, (Özet Bildiri) Sürdürülebilir Kalkınma

Insulinoma tumor model formation and possible marker determination

KARATUĞ KAÇAR A., BULUTAY P., Aylar D., Çelikten M., BOLKENT Ş.

BioTechBioChem 2021, 24 - 26 Kasım 2021, (Özet Bildiri)

The effects of targeted Dinutuximab beta monoclonal antibody on pancreatic beta cell toxicity

KARATUĞ KAÇAR A., ADIGÜZEL Z.

3rd International Cancer and Ion Channels Congress (CANCERION-2021), 16 Eylül 2021, (Özet Bildiri)

Different fractions of Salix babylonica L. leaf extract have different effects on insulin release in INS-1 cells

Aylar D., Kazdal F., BAHADORI F., KARATUĞ KAÇAR A.

3rd International Cancer and Ion Channels Congress (CANCERION-2021), 16 Eylül 2021, (Özet Bildiri)

Glukotoksisite, miR -335 ile Hedeflenen Runx2 ve İnsülin Aracılı Mekanizma Yoluyla Pankreatik Beta ve Kanal Hücre Fonksiyonlarının Bozulmasına Neden Olur

Oktayoğlu S., Sancar S., Karatuğ Kaçar A., Bolkent Ş.

İstinye Üniversitesi Kök Hücre ve Doku Mühendisliği Sempozyumu, İstanbul, Türkiye, 27 - 28 Şubat 2021, ss.86-87, (Özet Bildiri)

ESCULETIN ENHANCES CASPASE-DEPENDENT APOPTOTIC CELL DEATH AND INSULIN SECRETION IN INS-1 CELLS

Karatuğ Kaçar A.

Uluslararası Biyokimya Kongresi - 2018 / 29. Ulusal Biyokimya Kongresi, Muğla, Türkiye, 26 - 30 Ekim 2018, cilt.43, ss.5, (Özet Bildiri)

Borik Asit Uygulanmış Yeşil Çayla Muamele Edilen MCF-7 Hücrelerinde HSP70 ve HSP90'ın Anlatımları Üzerine Bir Araştırma

SEZEKLER I., ERSÖZ M., KARATUĞ KAÇAR A., COŞKUN Z. M.

Uluslararası Tarım, Çevre ve Sağlık Kongresi, Aydın, Türkiye, 26 - 28 Ekim 2018, ss.220, (Özet Bildiri)

Alpha-Lipoic Acid Stimulates Insulin Secretion and Causes Necrotic Cell Death Via Oxidative Stress

Karatuğ Kaçar A.

INTERNATIONAL EURASIAN CONFERENCE ONBIOLOGICAL AND CHEMICAL SCIENCES, Ankara, Türkiye, 26 - 27 Nisan 2018, ss.154, (Özet Bildiri)

The Effects of Camellia Sinensis Extract on Proliferation, Apoptosis, Oxidative Stress in INS1 Cells

Ersöz M., Karatuğ Kaçar A., Sezekler I., Coşkun Z. M.

International Biochemistry Congress – 2017 /28 th National Biochemistry Congress, Erzurum, Türkiye, 19 - 23 Eylül 2017, ss.70, (Özet Bildiri)

THE INSULINOMA CELLS ARE DEATH AS DESTINATION WITH NANOPARTICULARS LOADED ESCULETIN

KARATUĞ KAÇAR A., BAHADORİ F., KEPEKÇİ TEKKELİ Ş. E., TOPÇU G., BOLKENT Ş.

4th INTERNATIONAL CONFERENCE ON MATERIALS SCIENCE AND NANOTECHNOLOGY FOR NEXT GENERATION (MSNG2017), Sarajevo, Bosna-Hersek, 28 - 30 Haziran 2017, ss.125, (Özet Bildiri)

4-METHYLCATECOL INDUCES NECROTIC CELL DEATH BY JNK PATHWAY IN INSULINOMA INS-1 CELLS

Karatuğ Kaçar A., Bolkent Ş.

VI. INTERNATIONAL CONGRESS OF MOLECULAR MEDICINE, İstanbul, Türkiye, 22 - 25 Mayıs 2017, ss.267, (Özet Bildiri)

The effects of Atorvastatin on Renal Injury that occurs associated with Pulmonary Fibrosis

KARATUĞ KAÇAR A., YILDIRIM M., BOLKENT Ş., Öztay F.

15th International Congress of Histochemistry and Cytochemistry, Antalya, Türkiye, 18 - 21 Mayıs 2017, ss.451, (Tam Metin Bildiri)

THERAPEUTIC ROLE OF α-LIPOIC ACID, VITAMIN E ANDSELENIUM COMBINATION IN LIVER OF DIABETIC MICE

KARATUĞ KAÇAR A., ERTİK O., COŞKUN Z. M., BOLKENT H. S., YANARDAĞ R., BOLKENT Ş.

3rd International Conference on New Trends in Chemistry, Finlandiya, 28 - 30 Nisan 2017, (Özet Bildiri) Sürdürülebilir Kalkınma

Therapeutic Role of alfa Lipoic Acid, Vitamin E and Selenium Combination in Liver of Diabetic Mice

KARATUĞ KAÇAR A., ERTİK O., Çoşkun Z. M., BOLKENT H. S., YANARDAĞ R., BOLKENT Ş.

3 rd International Conference on New Trends in Chemistry, Helsinki, Finlandiya, 28 - 30 Nisan 2017, ss.78, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

4 Metilkatekol Sıçan İnsülinoma hücrelerinde INS 1 hücre fonksiyon kaybına ve apoptotik hücre ölümüne neden olur

Karatuğ Kaçar A., Bolkent Ş.

5. Ulusal Moleküler Biyoloji ve Biyoteknoloji Kongresi, Konya, Türkiye, 18 - 21 Temmuz 2016, ss.8, (Özet Bildiri)

Vitronectin, fibronectin and epidermal growth factor induces proliferation via JNK and ERK pathway in insulinoma INS-1 cells

KARATUĞ KAÇAR A., BOLKENT Ş.

The EMBO Meeting 2015, Birmingham, Birleşik Krallık, 5 - 08 Eylül 2015, ss.105, (Tam Metin Bildiri)

Comparison of Efficacy and Toxicity of Lipid Based and Polymeric Nano Drug Delivery Systems

Bahadori F., Dağ A., Tekkeli Ş. E., Topçu G., Karatuğ Kaçar A., Önyüksel H., et al.

4th Annual International Conference on Advances in Biotechnology, Dubai, Birleşik Arap Emirlikleri, 10 - 11 Mart 2014, ss.97-100, (Tam Metin Bildiri)

Influence of exogenous ghrelin on the kidney of newborn STZ-diabetic rats

Bolkent S., Saçan Ö., Bolkent S., KARATUĞ A., Turk N., YANARDAĞ R.

World Diabetes Congress, Melbourne, Avustralya, 2 - 06 Aralık 2013, ss.1, (Tam Metin Bildiri) Sürdürülebilir Kalkınma

The Role of Vitamin B6 on Liver Damage Induced with Valproic Acid

Karatuğ Kaçar A., Türkyılmaz İ. B., Bolkent Ş., Yanardağ R.

The FEBS Journal, Sankt-Peterburg, Rusya, 6 - 11 Temmuz 2013, ss.290, (Özet Bildiri)

The relation between NGF and activin A is important for triggering pancreatic b cell apoptosis

Oktayoğlu S., Karatuğ Kaçar A., Bolkent Ş.

The FEBS Journal, Sevilla, İspanya, 4 - 09 Eylül 2012, ss.145-146, (Özet Bildiri)

NGF regulates EGF NGF and insulin at the expression synthesis and secretion levels in beta cells of rats

Bolkent Ş., Oktayoğlu S., Karatuğ Kaçar A.

The FEBS Journal, Sevilla, İspanya, 4 - 09 Eylül 2012, ss.164, (Özet Bildiri)

Betacellulin is increased in absence of Nerve Growth Factor

Karatuğ Kaçar A., Oktayoğlu S., Bolkent Ş.

The FEBS Journal, Sevilla, İspanya, 4 - 09 Eylül 2012, ss.147, (Özet Bildiri)

Chard (Beta vulgaris L. var. cicla) extract ameliorates oxidative status in the kidney tissue of streptozotocin-induced diabetic rats

BOLKENT Ş., SAÇAN Ö., İpci Y., KARATUĞ A., Kabasakal L., Şener G., et al.

The 2nd Euro-Mediterrenean Conference Plant Natural Products: From Biodiversity to Bioindustry, Alexandria, Egypt,, Mısır, 1 - 04 Aralık 2011, (Tam Metin Bildiri) Sürdürülebilir Kalkınma