Res. Asst. PhD Özge SOYLU ETER

Metrics

Publication

Project

Intellectual Property

UN Sustainable Development Goals

Education Information

2014 - 2019

Doctorate

Istanbul University, Health Sciences Institute, Farmasötik Kimya Doktora Programı, Turkey

2009 - 2014

Postgraduate

Istanbul University, Faculty Of Pharmacy , Eczacılık, Turkey

Dissertations

2019

Doctorate

İnterlökin-1 İnhibitörü İlaç Adayı Yeni 5-(triflorometoksi)-1H-indol-2,3-dion 3-(4-feniltiyosemikarbazon) Türevlerinin Tasarımı, Sentezi ve Etkinliklerinin İncelenmesi

Istanbul University, Health Sciences Institute, Farmasötik Kimya Anabilim Dalı

Certificates, Courses and Trainings

2020

Eğiticinin Eğitimi

Education Management and Planning

İstanbul Üniversitesi Sürekli Eğitim Uygulama ve Araştırma Merkezi

2018

İyi Laboratuvar Uygulamaları Eğitimi

Quality Management

İstanbul Üni. İlaç Araştırma ve Uygulama Merkezi

2016

Uygulamalı Patent Yazma ve Tarama Eğitimi

Industrial Rights, Intellectual Property Rights, Patent, Licensing

İÜ 3B Tıbbi ve Endüstriyel Tasarım Laboratuvarı (TETLAB)

2015

Computer-Aided Drug Design Workshop

Education Management and Planning

Bahçeşehir Üniversitesi Tıp Fakültesi

Research Areas

Health Sciences

Pharmacology and Therapeutics

Professional Sciences

Pharmaceutical Chemistry

Academic Titles / Tasks

2015 - Continues

Research Assistant PhD

Istanbul University, Faculty of Pharmacy , Department of Professional Pharmaceutical Sciences

Non Academic Experience

2017 - Continues

WEB Management Commission

University, İstanbul University, Faculty of Pharmacy

Courses

Undergraduate

Temel Eczacılık Kurulu II (Organik Kimya)

Published journal articles indexed by SCI, SSCI, and AHCI

2023

Antiviral activity and molecular modeling studies on 1H-indole-2,3-diones carrying a naphthalene moiety

SOYLU ETER Ö., Duran G. N., Özbil M., GÖKTAŞ F., CİHAN ÜSTÜNDAĞ G., KARALI N. L.

JOURNAL OF MOLECULAR STRUCTURE , vol.1281, 2023 (SCI-Expanded)

2022

Synthesis and molecular modeling studies of 1-benzyl-2-indolinones as selective AChE inhibitors

Apaydln Ç. B., SOYLU ETER Ö., Eraslan-Elma P., ÖZSOY N., Karall N. L.

Future Medicinal Chemistry , vol.14, no.23, pp.1705-1723, 2022 (SCI-Expanded)

2022

A Mini-Review on the Synthesis of Substituted Isatins: from Early Approaches to Recent Advances with a Specific Focus on Sulfamoyl and Amino Derivatives

Temizer A. B., Koulani T., Soylu Eter Ö., Karalı N. L.

MINI-REVIEWS IN ORGANIC CHEMISTRY , vol.19, pp.1-15, 2022 (SCI-Expanded)

2022

Selective Cytotoxic Effects of 5-Trifluoromethoxy-1H-indole-2,3-dione 3-Thiosemi-carbazone Derivatives on Lymphoid-originated Cells

Danışman-Kalındemirtaş F., Erdem-Kuruca S., Akgün-Dar K., Karakaş Z., Soylu Ö., Karali N. L.

Anti-Cancer Agents in Medicinal Chemistry , vol.22, no.2, pp.349-355, 2022 (SCI-Expanded)

2021

Synthesis, molecular modelling and cholinesterase inhibitory effects of 2-indolinone based hydrazinecarbothioamides

Demir Yazıcı K., Apaydın Ç. B., Soylu Eter Ö., Özsoy N., Karalı N. L.

FUTURE MEDICINAL CHEMISTRY , vol.13, pp.2133-2151, 2021 (SCI-Expanded)

Articles Published in Other Journals

2021

Molecular and crystal structure of 1-methyl-5-trifluoromethoxy-1H-indole-2,3-dione 3-[4-(4-methoxyphenyl)thiosemicarbazone]

Eter O. S., Atioglu Z., Akkurt M., Ersanli C. C., Karalı N. L.

ISTANBUL JOURNAL OF PHARMACY , vol.51, no.1, pp.59-66, 2021 (ESCI)

2017

Alzheimer Hastalığı ve Tedavisinde Güncel Yaklaşımlar

SOYLU Ö., KARALI N. L.

Türkiye Klinikleri J Pharm Sci , vol.6, no.2, pp.94-109, 2017 (Peer-Reviewed Journal)

Refereed Congress / Symposium Publications in Proceedings

2019

Molecular modelling and antiviral activity of 1H-indole-2,3-dione derivatives carrying naphthalene moiety

SOYLU Ö., Duran G. N., Özbil M., GÖKTAŞ F., CİHAN ÜSTÜNDAĞ G., Naesens L., et al.

7th International BAU Drug Design Congress, İstanbul, Turkey, 19 - 21 December 2019, pp.100-103

2018

Identification of Novel Small Molecule Ligands Targeting Interleukin-1 Receptor by SPR-based Screening

Çetin R., SOYLU Ö., Sevinçli Z. Ş., KARALI N. L., Erman B., Orer H., et al.

6th International Congress of the Molecular Biology Association of Turkey, İzmir, Turkey, 5 - 08 September 2018, pp.117

2017

Alzheimer hastalığı ve tedavisinde güncel yaklaşımlar

SOYLU Ö., KARALI N. L.

3. Uluslararası İlaç ve Eczacılık Kongresi, İstanbul, Turkey, 26 - 29 April 2017, pp.867

Supported Projects

2019 - 2022

NOVEL NON-NUCLEOSIDE HEPATITIS-C RNA-DEPENDENT RNA POLYMERASE (NS5B) INHIBITORS THAT BIND TO THE ALLOSTERIC THUMB SITE II

TUBITAK Project

Gezginci H. M.(Executive), Karaman Mayack B., Şenol H., Köse A., Soylu Eter Ö., Apaydın Ç. B.

2018 - 2021

Sülfamoilfenil artığı taşıyan 1H-indol-2,3-dion 3-tiyosemikarbazon türevleri: Moleküler modelleme, sentez, yapı tayini, antikanser ve antiviral etki tayini

Project Supported by Higher Education Institutions

KARALI N. L. (Executive), BOZDAĞ M., NAESENS L., CİHAN ÜSTÜNDAĞ G., GÖKTAŞ F., APAYDIN Ç. B., et al.

2017 - 2019

İnterlökin-1 inhibitörü ilaç adayı yeni 5-(triflorometoksi)-1H-indol-2,3-dion 3-(4-feniltiyosemikarbazon) türevlerinin tasarımı, sentezi ve etkinliklerinin incelenmesi

Project Supported by Higher Education Institutions

KARALI N. L. (Executive), SOYLU Ö.

2016 - 2019

Özgün 2-indolinon bileşiklerinin anti-interlökin 1 ve kemoterapötik ekinlik gösteren ilaçlar olarak geliştirilmesi

TUBITAK Project

KARALI N. L. (Executive), GÖKTAŞ F., CİHAN ÜSTÜNDAĞ G., GÜL A., Müftüoğlu M.(Executive), Orer H., et al.

2017 - 2018

3-Sülfamoilfenil artığı taşıyan 1H-indol-2,3-dion 3-tiyosemikarbazon türevlerinin sentezi, CYP ve aromataz enzim aktivitelerinin tayini

Project Supported by Higher Education Institutions

KARALI N. L. (Executive), SOYLU Ö., ÖZSOY N., GÜRER-ORHAN H., İNCE E., ERASLAN ELMA P., et al.

2013 - 2016

Kaspaz-1 ve/veya kaspaz-3 inhibitörü 1H-İndol-2,3-dion 3-(N-sülfamoilfenil)tiyosemikarbazon türevleri: Tasarım, moleküler modelleme, sentez ve biyolojik inceleme

Project Supported by Higher Education Institutions

KARALI N. L. (Executive), GÖKTAŞ F., CİHAN ÜSTÜNDAĞ G., ERASLAN P., GÜL A., ERMAN B., et al.

Patent

2020

5-Fluoro/(Trifluoromethoxy)-2-Indolinone Derivatives

Patent

Pending / Applied, The Invention Recourse Number: PCT/TR2020/050104

Memberships / Tasks in Scientific Organizations

2018 - Continues

Türk Farmasötik ve Medisinal Kimya Derneği

Member

2017 - Continues

Türk Eczacıları Birliği

Member

Congress and Symposium Activities

19 December 2019 - 21 December 2019

7th International BAU Drug Design Congress

Attendee

İstanbul-Turkey

01 December 2019 - 01 December 2019

7th International BAU Drug Design Congress

Working Group

İstanbul-Turkey

01 October 2019 - 01 October 2019

VI. Türk Tıp Dünyası Kurultayı

Attendee

İstanbul-Turkey

01 September 2019 - 01 September 2019

12th AIMECS 2019 AFMC International Medicinal Chemistry Symposium

Attendee

İstanbul-Turkey

01 April 2018 - 01 April 2018

V. Ulusal Farmasötik Kimya Kongresi

Attendee

Erzurum-Turkey

01 April 2017 - 01 April 2017

3. Uluslararası İlaç ve Eczacılık Kongresi

Attendee

İstanbul-Turkey

01 October 2015 - 01 October 2015

3rd International BAU Drug Design Congress

Attendee

İstanbul-Turkey

Scholarships

2014 - 2019