Akademik Veri Yönetim Sistemi
5th International Eurasian Conference on Biological and Chemical Sciences (EurasianBioChem 2022), Ankara, Türkiye, 23 - 25 Kasım 2022, ss.113
Aging is a normal process in all living organisms due to the error-prone molecular processes that occur as a result of
changing environmental conditions over time. As a result of studies at the molecular level, it has been determined that the
cellular aging mechanisms between organisms are extremely common and conserved. Green tea has a very high
antioxidant activity compared to other teas obtained from the same plant. Considering the ratios of polyphenols, which
make up approximately 37% of its composition, it is striking that Epigallocatechin Gallate (EGCG) polyphenol is present
in the maximum amount; For this reason, the focus of studies on green tea is EGCG, which is considered the active
ingredient of green tea. In this study, the effect of EGCG, the active ingredient of green tea, on cellular aging was
investigated in Schizosaccharomyces pombe, which is accepted as a model organism, by evaluating parameters such as
lifespan, carbohydrate consumption, intracellular oxidation, and it was observed that EGCG delays aging and improves
some cellular parameters.