Prognostic Value of Antithrombin Levels in COVID-19 Patients and Impact of Fresh Frozen Plasma Treatment: A Retrospective Study

Anaklı, İlkay; Ergin Özcan, Perihan; Polat, Özlem; Orhun, Günseli; Alay, Gülçin; Tuna, Verda; Çeliksoy, Emre; Kılıç, Mehmet; Mercan, Mutlu; Ali, Achmet; Beşışık, Sevgi; Esen, Figen

doi:10.4274/tjh.galenos.2021.2020.0695

Prognostic Value of Antithrombin Levels in COVID-19 Patients and Impact of Fresh Frozen Plasma Treatment: A Retrospective Study

Anaklı İ., Ergin Özcan P., Polat Ö., Orhun G., Alay G. H., Tuna V., ...More

Turkish journal of haematology : official journal of Turkish Society of Haematology, vol.38, pp.15-21, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 38
Publication Date: 2021
Doi Number: 10.4274/tjh.galenos.2021.2020.0695
Journal Name: Turkish journal of haematology : official journal of Turkish Society of Haematology
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
Page Numbers: pp.15-21
Keywords: Antithrombin, COVID-19, Fresh frozen plasma, Hypercoagulopathy, Mortality, KAPPA-B ACTIVATION
Istanbul University Affiliated: Yes

Abstract

Objective: The defective interplay between coagulation and inflammation may be the leading cause of intravascular coagulation and organ dysfunction in coronavirus disease-19 (COVID-19) patients. Abnormal coagulation profiles were reported to be associated with poor outcomes. In this study, we assessed the prognostic values of antithrombin (AT) activity levels and the impact of fresh frozen plasma (FFP) treatment on outcome.