Akademik Veri Yönetim Sistemi
14th Asia Pacific Musculoskeletal Tumor Society Meeting, Taipei, Tayvan, 04 Ekim 2023, ss.120-121
METASTATIC BONE DISEASES AND CRYOABLATION
Assoc Prof. AhmetSalduz
1
1Istanbul University
Objectives:
, MD Serkan Bayram1, Dr. Abdullah Kahraman1
Our aim is to present our experience of cryoablation in metastatic bone disease. Cryoablation is used for inducing
apoptosis of metastatic malign cells through the effect of coldness. Although its usage was limited when it was
introduced first, it’s getting more and more popular over time and found very effective in carefully selected groups
of patients.
Methods:
We would like to present 4 patients who have metastatic bone disease and are suitable for cryoablation therapy in
our clinic Istanbul University, Istanbul Medicine Faculty, Orthopaedics and Traumatology Department in the year
2022.We used IceCure (the company of cryoprobe technology) systems to treat such patients. Cryoprobe has a
cooling center at the distal end of the probe and that forms a lethal area around itself. It has different options in
terms of needle gauge and diameter of lethal area. The cooling center can create temperatures up to -170 °C and it
is usually performed under CT guidance. The primary diagnoses of our patients were thyroid ca (1 patient), breast ca
(1 patient), cervix ca (1 patient) and anal squamose cell cancer (SCC) (1 patient).
Results:
The mean age of the patients was 43.3 years (range 34-60 years). And mean follow-up time was 12 (9-15) months.
The first application was performed in the posterior iliac spine which has thyroid ca isolated metastasis. This patient
has perfect results with a metabolic and anatomic response on PET-CT after 4 months (Figure 1). The second
application was performed into the glenoid ac coracoid process which has breast ca metastasis. Follow-up PET-CT
shows almost complete regression with satisfactory shoulder function (Figure 2). The third application was
performed in the ischial ramus which has cervical ca metastasis. Figure 3 shows a good example of ice-ball on CT
during the application. The fourth application was performed into the left acetabular area which has anal SCC
metastasis.
Conclusions:
Cryoablation is a safe, minimally invasive, and effective treatment option for bone metastasis in selected patients. It
could be used for palliative or curative intent.