CD133+cells are associated with ADIPOCYTOKINES and endothelial dysfunction in hemodialysis patients

Ozkok A., Atas R., Cinar S. A., Yilmaz A., Aktas E., Deniz G., ...More

BMC NEPHROLOGY, vol.18, 2017 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 18
  • Publication Date: 2017
  • Doi Number: 10.1186/s12882-017-0663-x
  • Journal Name: BMC NEPHROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Keywords: CD133+cells, Adipocytokines, Leptin, Adiponectin, Resistin, Tumor necrosis factor-alpha, Interleukin-6, Flow-mediated dilatation, Endothelial dysfunction, Atherosclerosis, INTIMA-MEDIA THICKNESS, INSULIN-RESISTANCE, ADIPOSE-TISSUE, INFLAMMATION, CELLS, LEPTIN, DISEASE, CD133, ADIPONECTIN, OBESITY
  • Istanbul University Affiliated: Yes


Background: Hemodialysis (HD) patients have increased risk of cardiovascular disease (CVD). Impaired stem cell health and adipocytokine metabolism may play important roles in the complex pathophysiological mechanisms of CVD in this patient population. We aimed to investigate the relationships between CD133+ cell counts, adipocytokines and parameters of endothelial dysfunction and atherosclerosis in HD patients.