The effect of anti-human leukocyte antigen, anti-major histocompatibility complex class 1 chain-related antigen a, and anti-glutathione transferase-T1 antibodies on the long-term survival of renal allograft.


Akgul S. U., Oguz F., Caliskan Y., Kekik Ç., Cagatay P., Turkmen A., ...More

Transplantation proceedings, vol.45, no.3, pp.890-4, 2013 (SCI-Expanded) identifier identifier identifier

Abstract

Background. One of the most important mechanisms of allograft rejection is the production of donor-specific antibodies (DSA). Anti-major histocompatibility complex class-I chain-related antigen A (MICA) and anti-glutathione S transferase-T1 (GSTT1) antibodies cause graft dysfunction and reduce graft survival. The aim of this study was to examine the effects of anti-human leukocyte antigen class I-II, anti-MICA, and anti-GSTT1 antibodies in development of antibody-mediated rejection.