The combination of nterleukin-10-1082 and tumor necrosis factor alpha-308 or interleukin-6-174 genes polymorphisms suggests an association with susceptibility to Hashimoto's thyroiditis

Baki, Adile; Akman, Fevziye; Vural, Pervin; Dogru-Abbasoglu, Semra; OZDERYA, Aysenur; KARADAG, Berrin; Uysal, Mujdat

doi:10.1016/j.intimp.2012.02.003

The combination of nterleukin-10-1082 and tumor necrosis factor alpha-308 or interleukin-6-174 genes polymorphisms suggests an association with susceptibility to Hashimoto's thyroiditis

Atıf İçin Kopyala

Baki M., Akman F. E., Vural P., Dogru-Abbasoglu S., OZDERYA A., KARADAG B., ...Daha Fazla

INTERNATIONAL IMMUNOPHARMACOLOGY, cilt.12, sa.4, ss.543-546, 2012 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 12 Sayı: 4
Basım Tarihi: 2012
Doi Numarası: 10.1016/j.intimp.2012.02.003
Dergi Adı: INTERNATIONAL IMMUNOPHARMACOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.543-546
İstanbul Üniversitesi Adresli: Evet

Özet

Background: The etiopathogenesis of Hashimoto's thyroiditis (HT) has not been clearly elucidated although the role of chronical inflammation and endothelial dysfunction has been established. The imbalance between pro- and anti-inflammatory cytokines may play a role in the etiology. The aim of the present study was to investigate whether cytokine gene polymorphisms are associated with HT, and to evaluate the relationship between genotypes and clinical/laboratory manifestation of HT.