Increased frequency of the S-allele of the L-myc oncogene in breast cancer

ISBIR T., Yaylim I., ARIKAN S., KUCUCUK S., CAMLICA H.

MOLECULAR MEDICINE, cilt.8, sa.9, ss.521-524, 2002 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 9
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1007/bf03402161
  • Dergi Adı: MOLECULAR MEDICINE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.521-524
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Association between restriction fragment length polymorphisms (RFLP) of known oncogenes and a predisposition to develop cancer have been postulated. The L-myc gene is a potential molecular marker associated with cancer susceptibility as well as metastasis, prognosis, and adverse survival. Our aim was to test the hypothesis that there was an association between L-myc S allele in breast cancer and a predisposition to the disease.