Akademik Veri Yönetim Sistemi
Turkish Association of Oral and Maxillofacial Surgery 26th International Scientific Congress, Girne, Kıbrıs (Kktc), 28 Nisan - 02 Mayıs 2019, ss.187-188
Objective: Neural lesions in the oral region are rare. Neurofibroma originating from Schwann cells
and perineuronal fibroblasts is a benign neural tumor. Neurofibromatosis, also known as Von
Recklinghausen disease, is an autosomal dominant disease affecting many organs. Although it
usually shows skin involvement, oral involvement may be seen in 10-25% of patients.
Neurofibromas have a 8-13% risk of malignant transformation.
Case: A 34-year-old female patient with neurofibromatosis type 1 referred the Istanbul University
Department of Oral and Maxillofacial Surgery. There was a lesion at right maxilla between canine
and first premolar for 15 years which was smooth, swelling vestibule, regular border, looks like
lipoma. Panoramic radiograph showed a regular radiolucent lesion. Cone-beam computed
tomography showed a cut-off in the palatinal cortical border. The lesion was enucleated under local
anesthesia. Histopathological examination revealed neurofibroma.
Conclusion: neural lesions may be confused with non-ulcerated tissue proliferation in the oral
region. Correct anamnesis and histopathological examination are important. The patient was
followed-up regularly due to risk of malignant transformation.