Comparison of new and classical point mutations associated with clarithromycin resistance in Helicobacter pylori strains isolated from dyspeptic patients and their effects on phenotypic clarithromycin resistance


KOCAZEYBEK B. S., Sakli M. K., Yuksel P., DEMİRCİ M., Caliskan R., Sarp T. Z., ...Daha Fazla

JOURNAL OF MEDICAL MICROBIOLOGY, cilt.68, sa.4, ss.566-573, 2019 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 68 Sayı: 4
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1099/jmm.0.000944
  • Dergi Adı: JOURNAL OF MEDICAL MICROBIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.566-573
  • Anahtar Kelimeler: Helicobacter pylori, A2115G, A2144T and G2141A, point mutations, clarithromycin, RIBOSOMAL-RNA GENE, ANTIBIOTIC-RESISTANCE, MACROLIDE RESISTANCE, METRONIDAZOLE, PREVALENCE, ASSAY, RISK
  • İstanbul Üniversitesi Adresli: Evet

Özet

Purpose. We aimed to investigate the presence of three recently identified point mutations (A2115G, G2141A and A2144T) of the 23 S rRNA gene and compare them with the three most frequently encountered point mutations (A2142G, A2142C and A2143G) in Helicobacter pylori strains in Turkey.