Chemokine and Chemokine Receptor Polymorphisms in Bipolar Disorder

Tokaç D., Tuzun E., GULEC H., Yilmaz V., Bireller E. S., Cakmakoglu B., ...More

PSYCHIATRY INVESTIGATION, vol.13, no.5, pp.541-548, 2016 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.4306/pi.2016.13.5.541
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Social Sciences Citation Index (SSCI), Scopus
  • Page Numbers: pp.541-548
  • Istanbul University Affiliated: Yes


Objective Bipolar disorder (BD) is a debilitating psychiatric disease with unknown etiology. Recent studies have shown inflammation as a potential contributing factor of BD pathogenesis. However, potential associations between chemokine and chemokine receptor polymorphisms and BD have been fundamentally understudied. To identify participation of chemokines in BD pathogenesis, we examined genetic variants of several chemokine and chemokine receptor genes.