Chemokine and Chemokine Receptor Polymorphisms in Bipolar Disorder


Tokaç D., Tuzun E. , GULEC H., Yilmaz V., Bireller E. S. , Cakmakoglu B. , ...More

PSYCHIATRY INVESTIGATION, vol.13, no.5, pp.541-548, 2016 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 13 Issue: 5
  • Publication Date: 2016
  • Doi Number: 10.4306/pi.2016.13.5.541
  • Title of Journal : PSYCHIATRY INVESTIGATION
  • Page Numbers: pp.541-548

Abstract

Objective Bipolar disorder (BD) is a debilitating psychiatric disease with unknown etiology. Recent studies have shown inflammation as a potential contributing factor of BD pathogenesis. However, potential associations between chemokine and chemokine receptor polymorphisms and BD have been fundamentally understudied. To identify participation of chemokines in BD pathogenesis, we examined genetic variants of several chemokine and chemokine receptor genes.