Serum endotrophin levels in patients with heart failure with reduced and mid-range ejection fraction.

Eruzun H., Toprak İ. D., Arman Y., Yilmaz U., Ozcan M., Kutlu Y., ...Daha Fazla

European journal of internal medicine, cilt.64, ss.29-32, 2019 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 64
  • Basım Tarihi: 2019
  • Doi Numarası: 10.1016/j.ejim.2019.04.016
  • Dergi Adı: European journal of internal medicine
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.29-32
  • Anahtar Kelimeler: Endotrophin, Renin angiotensin aldosterone system, Fibrosis, Heart failure, ANGIOTENSIN-CONVERTING ENZYME, MYOCARDIAL FIBROSIS, VI COLLAGEN, ALDOSTERONE, SECONDARY, STIFFNESS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Endotrophin, a type VI collagen cleavage product, has fibrosis, and insulin resistance effects. Type VI collagen also plays a role in cardiac fibrosis. In this study, we aimed to investigate the role of endotrophin in the pathogenesis of cardiac fibrosis by determining its levels in patients with heart failure with reduced and mid-range ejection fraction (EF). We also aimed to determine the possible association between endotrophin and treatment that prevents ventricular fibrosis.