THE UTILITY OF HISTOMORPHOLOGICAL FEATURES IN THE DIFFERENTIATION OF EOSINOPHILIC CHROMOPHOBE RENAL CELL CARCINOMA AND ONCOCYTOMA.

Mete O., KILIÇASLAN I., Uysal V.

TURKISH JOURNAL OF PATHOLOGY, cilt.21, sa.3-4, ss.62-66, 2005 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 21 Sayı: 3-4
  • Basım Tarihi: 2005
  • Dergi Adı: TURKISH JOURNAL OF PATHOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.62-66
  • Anahtar Kelimeler: Renal cell carcinoma, oncocytoma
  • İstanbul Üniversitesi Adresli: Evet

Özet

Renal oncocytomas and eosinophilic variants of chromophobe renal cell carcinomas have similar histological and cytological features. In order to identify some histological parameters for differentiating these tumours, 51 renal oncocytomas and 32 chromophobe renal cell carcinoma were included in our study. Nuclear, cytoplasmic, structural and stromal features are investigated in both tumours. The presence of well-defined nuclear border, fibrohyalinised scar, stromal oedema and entrapped tubules are found to be significant (p<0,05) for oncocytomas. The presence of necrosis, perinuclear halo and special vascular network are found to be significant (p<0,05) in chromophobe renal cell carcinomas.