Decreased prohepcidin levels in patients with HBV-related liver disease: relation with ferritin levels.


Yonal O., Akyuz F., Demir K., Ciftci S., Keskin F., Pinarbasi B., ...More

Digestive diseases and sciences, vol.55, no.12, pp.3548-51, 2010 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 12
  • Publication Date: 2010
  • Doi Number: 10.1007/s10620-010-1183-8
  • Journal Name: Digestive diseases and sciences
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3548-51
  • Keywords: Prohepcidin, Iron, Hepatitis B, Cirrhosis, CHRONIC HEPATITIS-C, IRON-METABOLISM, HEPCIDIN EXPRESSION, INFLAMMATION, CIRRHOSIS
  • Istanbul University Affiliated: Yes

Abstract

Levels of prohepcidin, a homeostatic regulator of iron absorption, are altered in chronic hepatitis C and liver cirrhosis. However, data on the potential alterations of prohepcidin in patients with HBV-related liver disease are scarce. We investigated whether serum prohepcidin is related to iron overload and perenchymal dysfuction in HBV-related liver disease.