Decreased prohepcidin levels in patients with HBV-related liver disease: Relation with ferritin levels

Yonal O., Akyuz F. , Demir K., Ciftci S. , Keskin F. , Pinarbasi B., ...More

Digestive Diseases and Sciences, vol.55, no.12, pp.3548-3551, 2010 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 55 Issue: 12
  • Publication Date: 2010
  • Doi Number: 10.1007/s10620-010-1183-8
  • Title of Journal : Digestive Diseases and Sciences
  • Page Numbers: pp.3548-3551


Levels of prohepcidin, a homeostatic regulator of iron absorption, are altered in chronic hepatitis C and liver cirrhosis. However, data on the potential alterations of prohepcidin in patients with HBV-related liver disease are scarce. We investigated whether serum prohepcidin is related to iron overload and perenchymal dysfuction in HBV-related liver disease.