Adaptive immunity cells are differentially distributed in the peripheral blood of glycine receptor antibody-positive patients with focal epilepsy of unknown cause.

Sanli, Elif; Akbayir, Ece; Kuçukali, Cem; Baykan, Betül; Sirin, Nermin; Bebek, Nerses; Yilmaz, Vuslat; Tuzun, Erdem

doi:10.1016/j.eplepsyres.2020.106542

Adaptive immunity cells are differentially distributed in the peripheral blood of glycine receptor antibody-positive patients with focal epilepsy of unknown cause.

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Sanli E., Akbayir E., Kuçukali C. İ., Baykan B., Sirin N. G., Bebek N., ...More

Epilepsy research, vol.170, pp.106542, 2021 (SCI-Expanded)

Publication Type: Article / Article
Volume: 170
Publication Date: 2021
Doi Number: 10.1016/j.eplepsyres.2020.106542
Journal Name: Epilepsy research
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Abstracts in Social Gerontology, BIOSIS, CAB Abstracts, EMBASE, MEDLINE, Veterinary Science Database
Page Numbers: pp.106542
Istanbul University Affiliated: Yes

Abstract

Aim: Glycine receptor (GlyR) autoantibodies (Ab) have been recently detected in epilepsy patients. Our study aimed to investigate the peripheral blood distribution of B and T cell subgroups responsible for antibody production to find clues supporting the distinct organization of adaptive immunity in focal epilepsy of unknown cause (FEUC).