Atıf İçin Kopyala
Gurdol F., Yurdum L. M., Ozturk U., Isbilen E., Cakmakoglu B.
ARCHIVES OF GYNECOLOGY AND OBSTETRICS, cilt.286, sa.1, ss.51-54, 2012 (SCI-Expanded)
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Yayın Türü:
Makale / Tam Makale
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Cilt numarası:
286
Sayı:
1
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Basım Tarihi:
2012
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Doi Numarası:
10.1007/s00404-012-2244-3
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Dergi Adı:
ARCHIVES OF GYNECOLOGY AND OBSTETRICS
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Derginin Tarandığı İndeksler:
Science Citation Index Expanded (SCI-EXPANDED), Scopus
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Sayfa Sayıları:
ss.51-54
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Anahtar Kelimeler:
Chemokines, Polymorphism, Preeclampsia, Receptor, PROMOTER POLYMORPHISM, EXPRESSION, GENE, RESISTANCE, CYTOKINES, RISK, PREGNANCY, DNA
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İstanbul Üniversitesi Adresli:
Evet
Özet
Endothelial dysfunction and inflammation are involved in the pathogenesis of preeclampsia. The CC chemokine receptor 5 (CCR5) modulates inflammation secondary to endothelial dysfunction and related vascular disorders, by initiating chemotaxis. In this study, we examined the frequency of two polymorphisms, the CCR5 Delta 32 deletion and the CCR5-59029 A/G promoter point mutation in women with preeclampsia.