IMPLICATION OF SERUM IL-17 LEVELS IN CHRONIC HEPATITIS B PATIENTS

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ÇAKAL B., ÇAVUŞ B., Atasoy A., Ormeci A., BULAKÇI M., GÜLLÜOĞLU M., ...Daha Fazla

JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI, cilt.84, sa.1, ss.68-75, 2021 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 84 Sayı: 1
  • Basım Tarihi: 2021
  • Doi Numarası: 10.26650/iuitfd.2020.0094
  • Dergi Adı: JOURNAL OF ISTANBUL FACULTY OF MEDICINE-ISTANBUL TIP FAKULTESI DERGISI
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.68-75
  • Anahtar Kelimeler: Hepatitis B virus, Chronic hepatitis B, Fibrosis stage, Interleukin-17, INCREASED TH17 CELLS, DISEASE PROGRESSION, LIVER FIBROSIS, STELLATE CELLS, INFLAMMATION, EXPRESSION, CONTRIBUTE, FREQUENCY, SEVERITY, THERAPY
  • İstanbul Üniversitesi Adresli: Evet

Özet

Objective: Natural course and clinical outcomes of chronic hepatitis B virus (HBV) infection is closely releated to immun responses of host and viral factors. Studies have suggested that there is strongly correlation between the level of IL-17 and especially of advanced liver damages associated with HBV. Role of IL-17 on natural course of chronic hepatitis B disease is yet to be fully clarified. This study aimed to evaluate the correlation between serum IL-17 levels with histological, virological, serological and biochemical data of chronic hepatitis B patients.