The impact of platelet membrane glycoprotein Ib alpha and Ia/IIa polymorphisms on the risk of thrombosis in the antiphospholipid syndrome


Yonal I. , Hindilerden F., Hancer V. S. , Artim-Esen B. , Daglar A. , Akadam B., ...More

Thrombosis Research, vol.129, no.4, pp.486-491, 2012 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 129 Issue: 4
  • Publication Date: 2012
  • Doi Number: 10.1016/j.thromres.2011.10.005
  • Title of Journal : Thrombosis Research
  • Page Numbers: pp.486-491

Abstract

Background: Pathogenesis of thrombus formation in antiphospholipid syndrome (APS) is not clear. Platelet membrane glycoprotein (GP) receptors play important roles in development of thrombosis. Objectives: We investigated the association between development of thrombosis in APS and polymorphisms of GPIb alpha variable number of tandem repeats (VNTR), Kozak, and GPIa C807T.