Dielectric Spectroscopy Application on biyolojical cells


Değer D., Ulutaş H. K., Yakut Ş., Uygun N., Oruç E.

9.Liquid Matter Conference, Lisbon, Portugal, 21 - 25 July 2014, pp.391

  • Publication Type: Conference Paper / Full Text
  • City: Lisbon
  • Country: Portugal
  • Page Numbers: pp.391
  • Istanbul University Affiliated: Yes

Abstract

This study aims to present an alternative diagnostic technique in order to differ healthy biological cells and tissues from infected cells and tissues. For this purpose,
dielectric spectroscopy measurements was applied infected fluid samples from pleura of lungs. Samples were placed between electrodes such as Al and gold.
Dielectric spectroscopy measurements were done at low pressure with 10-2 Torr at room temperature. The applied frequency interval was between 0,1Hz and 20MHz.
For evaluation of dielectric behaviour of investigated samples, frequency dependence of dielectric constant, dielectric loss and AC conductivity were focused on. At
low frequency region the effect of interfacial polarization was observed. The change of the dominant polarization mechanism in sample was observed at different
frequencies as a step-like behaviour of dielectric constant. Similar behaviour appeared in dielectric loss behaviour as different relaxation peaks at different
frequencies. When the AC conductivity was investigated, it was shown that the conductivity mechanism changes depending on the frequency of applied field. This
result may cause from diffent type of polarized entities such as infected cells or infected tissues. One of the main parameter was effect of time derivation for sample
fluids.