Effect of haemodiafiltration vs conventional haemodialysis on growth and cardiovascular outcomes in children - the HDF, heart and height (3H) study

Shroff, Rukshana; Bayazit, Aysun; STEFANIDIS, Constantinos; ASKITI, Varvara; Azukaitis, Karolis; Canpolat, Nur; Agbas, Ayse; Anarat, Ali; AOUN, Bilal; Bakkaloglu, Sevcan; Bhowruth, Devina; BORZYCH-DUZALKA, Dagmara; Bulut, Ipek; BUESCHER, Rainer; Dempster, Claire; Duzova, Ali; HABBIG, Sandra; Hayes, Wesley; HEGDE, Shivram; KRID, Saoussen; Licht, Christoph; LITWIN, Mieczyslaw; Mayes, Mark; Mir, Sevgi; Nemec, Rose; OBRYCKI, Lukasz; PAGLIALONGA, Fabio; PICCA, Stefano; RANCHIN, Bruno; SAMAILLE, Charlotte; SHENOY, Mohan; SINHA, Manish; Smith, Colette; SPASOJEVIC, Brankica; VIDAL, Enrico; VONDRAK, Karel; Yilmaz, Alev; ZALOSZYC, Ariane; FISCHBACH, Michel; SCHAEFER, Franz; SCHMITT, Claus

doi:10.1186/s12882-018-0998-y

Effect of haemodiafiltration vs conventional haemodialysis on growth and cardiovascular outcomes in children - the HDF, heart and height (3H) study

Atıf İçin Kopyala

Shroff R., Bayazit A., STEFANIDIS C. J., ASKITI V., Azukaitis K., Canpolat N., ...Daha Fazla

BMC NEPHROLOGY, cilt.19, 2018 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 19
Basım Tarihi: 2018
Doi Numarası: 10.1186/s12882-018-0998-y
Dergi Adı: BMC NEPHROLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Anahtar Kelimeler: Haemodialysis (HD), Haemodiafiltration (HDF), Children, Cardiovascular, Growth, Carotid intima media thickness (IMT), INTIMA-MEDIA THICKNESS, CHRONIC KIDNEY-DISEASE, ALL-CAUSE MORTALITY, ONLINE-HEMODIAFILTRATION, VASCULAR CALCIFICATION, PEDIATRIC-PATIENTS, DIALYSIS PATIENTS, REFERENCE VALUES, BLOOD-PRESSURE, VOLUME
İstanbul Üniversitesi Adresli: Evet

Özet

Background: Cardiovascular disease is prevalent in children on dialysis and accounts for almost 30% of all deaths. Randomised trials in adults suggest that haemodiafiltration (HDF) with high convection volumes is associated with reduced cardiovascular mortality compared to high-flux haemodialysis (HD); however paediatric data are scarce. We designed the haemodiafiltration, heart and height (3H) study to test the hypothesis that children on HDF have an improved cardiovascular risk profile, growth and nutritional status and quality of life, compared to those on conventional HD.