Evaluation of Paclitaxel Effects in The Pattern of Expression of Survival and Apoptotic Genes Regulators in HeLa Cells

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Atıf İçin Kopyala

Serbes U., Ozsoylemez O. D., Ozcan G.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY, cilt.17, sa.12, ss.1058-1067, 2016 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 17 Sayı: 12
• Basım Tarihi: 2016
• Doi Numarası: 10.2174/1389201017666160914190550
• Dergi Adı: CURRENT PHARMACEUTICAL BIOTECHNOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.1058-1067
• İstanbul Üniversitesi Adresli: Evet

Özet

We aim to determine the regulation of apoptosis by paclitaxel-induced and understand cancer dynamics to treatment targets for HeLa cells by identifying decrease/increase genes expression on HeLa cells. In this study, the anti-tumor effects of Paclitaxel (PAC) on HeLa cells have been studied in order to determine the cellular and molecular mechanisms of these effects.