Quantitative detection of methylated SOCS-1 in schizophrenia and bipolar disorder considering SOCS-1-1478CA/del polymorphism and clinical parameters

Aytac H. M., Pehlivan S., Pehlivan M., Oyaci Y.

IRISH JOURNAL OF MEDICAL SCIENCE, cilt.192, sa.2, ss.775-783, 2023 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 192 Sayı: 2
  • Basım Tarihi: 2023
  • Doi Numarası: 10.1007/s11845-022-03030-w
  • Dergi Adı: IRISH JOURNAL OF MEDICAL SCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.775-783
  • Anahtar Kelimeler: Bipolar disorder, DNA methylation, PCR-RFLP, qMS-PCR, Schizophrenia, SOCS-1, TOXOPLASMA-GONDII, JAK/STAT PATHWAY, RATING-SCALE, SERUM-LEVELS, ASSOCIATION, BLOOD, GENE, INFLAMMATION, RELIABILITY, SUPPRESSOR
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background We aimed to investigate the quantitative detection of methylated suppressor of cytokine signaling-1 (SOCS-1) in schizophrenia (SCZ) and bipolar disorder (BD), considering SOCS-1 -1478CA/del polymorphism and clinical parameters.