G-protein Coupled Estrogen Receptor Expression in Growth Hormone Secreting and Non-Functioning Adenomas.

Ozkaya, Hm; Sayitoglu, Müge; Comunoglu, N; Sun, E; Keskin, Fe; Ozata, D; Hocaoglu, Rh; Khodzaev, K; Firtina, S; Tanriover, N; Gazioglu, N; Oz, B; Kadioglu, P

doi:10.1055/a-1274-1330

G-protein Coupled Estrogen Receptor Expression in Growth Hormone Secreting and Non-Functioning Adenomas.

Ozkaya H., Sayitoglu M. , Comunoglu N., Sun E., Keskin F., Ozata D., ...More

Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, vol.129, pp.634-643, 2021 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 129
Publication Date: 2021
Doi Number: 10.1055/a-1274-1330
Title of Journal : Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
Page Numbers: pp.634-643
Keywords: acromegaly, aromatase, estrogens, hormones, GPER1, pituitary tumor, TUMOR-TRANSFORMING GENE, AROMATASE ENZYME EXPRESSION, HUMAN PITUITARY, IMMUNOHISTOCHEMICAL EXPRESSION, IN-VITRO, CANCER, LOCALIZATION, GPER, ACTIVATION, TAMOXIFEN

Abstract

Purpose To evaluate the expression of G-protein coupled estrogen receptor (GPER1), aromatase, estrogen receptor alpha (ER alpha), estrogen receptor beta (ER beta), pituitary tumor transforming gene (PTTG), and fibroblast growth factor 2 (FGF2) in GH-secreting and non-functioning adenomas (NFA).