Angiotensin Receptor Neprilysin Inhibition Compared With Enalapril on the Risk of Clinical Progression in Surviving Patients With Heart Failure


Packer M. , McMurray J. J. V. , Desai A. S. , Gong J., Lefkowitz M. P. , Rizkala A. R. , ...More

CIRCULATION, vol.131, no.1, pp.54-61, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 131 Issue: 1
  • Publication Date: 2015
  • Doi Number: 10.1161/circulationaha.114.013748
  • Title of Journal : CIRCULATION
  • Page Numbers: pp.54-61
  • Keywords: heart failure, neprilysin, receptors, angiotensin, LEFT-VENTRICULAR DYSFUNCTION, NATRIURETIC-PEPTIDE, NEUTRAL ENDOPEPTIDASE, CONVERTING ENZYME, MYOCARDIAL-INFARCTION, MILD SYMPTOMS, ADRENOMEDULLIN, MORTALITY, EPLERENONE, METABOLISM

Abstract

Background-Clinical trials in heart failure have focused on the improvement in symptoms or decreases in the risk of death and other cardiovascular events. Little is known about the effect of drugs on the risk of clinical deterioration in surviving patients.