Akademik Veri Yönetim Sistemi
PRES 2022, Praha, Çek Cumhuriyeti, 20 - 23 Eylül 2022, ss.36-37
Introduction: Juvenile psoriatic arthritis (JPsA) is one of the 7
subtypes of juvenile idiopathic arthritis (JIA) according to the
International League of Associations for Rheumatology (ILAR)
classification criteria. JPsA is the rarest subgroup of JIA, so the
corresponding literature describing the clinical characteristics, longterm outcomes, or treatment status of JPsA is limited
Objectives: To describe demographic and clinical features of children
with JPsA and to compare distinct patterns of the disease between
early onset and late onset groups.
Methods: Patients classified as JPsA according to ILAR criteria in 7
different pediatric rheumatology centers and followed regularly for
at least 6 months between 2010 and 2020 were included in the
study. The files of the patients were reviewed retrospectively, and
their demographic, clinical and treatment characteristics were
evaluated.
Results: A total of 87 (46 male/41 female) patients were included in
the study. The mean age at diagnosis of JPsA was 11.9 ± 4.5. While
57 (65.5%) of the patients had psoriasis at the time of diagnosis,
arthritis preceded psoriasis in 10 (11.5%) patients. There were 32
(36.8%) patients with a history of psoriasis in the first-degree relatives. Thirty (34.5%) patients had dactylitis, 28 (32.2%) had nail pitting, 36 (41.4%) had small joint involvement, 20 (23%) had enthesitis,
and 14 (16.1%) had axial involvement. Sacroiliitis was detected in 11
(12.6%) patients on magnetic resonance imaging. Uveitis developed
in 4 (4.5%) patients during the follow-up period. Anti- nuclear antibodies (ANA) were positive in 35 (40.2%) patients. Twelve children
were in the early-onset (<5 years) group. Uveitis and ANA positivity
were more common in the early early-onset group.
Conclusion: About one-third of patients with JPsA do not have psoriasis at the time of diagnosis. In some patients, no skin lesion is seen
during the course of the disease. Children with psoriatic arthritis
seem to displaying two different phenotypes. Younger children tend
to have female predominance, ANA positivity and uveitis, while older
children have more axial involvement