The increased transglutaminase 2 expression levels during initial tumorigenesis predict increased risk of metastasis and decreased disease-free and cancer-specific survivals in renal cell carcinoma.

Erdem S., Yegen G., Telci D., Yildiz I., Tefik T., Issever H., ...More

World journal of urology, vol.33, no.10, pp.1553-60, 2015 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 33 Issue: 10
  • Publication Date: 2015
  • Doi Number: 10.1007/s00345-014-1462-7
  • Journal Name: World journal of urology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.1553-60
  • Keywords: Renal cell carcinoma, Transglutaminase 2, Tumor marker, Metastasis, TISSUE TRANSGLUTAMINASE, ADHESION
  • Istanbul University Affiliated: Yes


The aim of this study was to investigate the role of transglutaminase 2(TG2) in renal cell carcinoma (RCC) by comparing the immunohistochemistry staining of primary and metastatic tumor tissues.