Association of MDR1 Gene Polymorphism in Patients With Temporal Lobe Epilepsy

ÇİNE N., Sargin G., Bebek N., Gurses C., Baykan B., Ozbek U., ...More

JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH, vol.30, no.1, pp.4-11, 2013 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 30 Issue: 1
  • Publication Date: 2013
  • Journal Name: JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.4-11
  • Istanbul University Affiliated: Yes

Abstract

Objective: 30-40% of patients with epilepsy have resistance to medical treatment. The major genetic mechanism postulated to underlie this resistance known as Multidrug resistance gene 1 (MDR1), transports the drugs from intracellular to extracellular area.