8. Uluslararası Katılımlı Türk Toksikoloji Derneği Kongresi, Antalya, Turkey, 1 - 04 November 2012, pp.82-83
Riot control agents are highly potent irritants, that are called as “lacrimators” or “tear gases”. These chemicals interacts with sensory neurons and present site-spesific and time-dependent toxicity. At the site of exposure area, eyes or skin, it causes pain and irritation. The most commonly available riot control agent is “Oleoresin capsicum”, best known as “Pepper spray”. These formulation contains different amounts of Capsicum annuum or Capsicum frutescenes as main ingredent. The Oleoresin capsicum contains an organic compound that called capsaicinoids. o-Chlorobenzylidene malononitrile and 2-chloroacetophenone are synthetic organic chemicals. These extracts have mainly ocular and dermal effects and the other effects are on respiratory system, nervous system, mucosa membranes and reproductive system. Pepper sprays active ingredients may associated with public health risk. In this review we discussed chemical characteristics, systemic and local effects and the toxic effects on several systems of pepper spray and its compounds.