Interleukin-12 and Protamine Inhibit Angiogenesis and Growth of C6 Rat Glioma: Synergistic Effects and Role of Th2 Cells

TURNA, AKİF; KIRAN, BAYRAM; Ozar, Engin; TURNA, ZEYNEP; Mercan, Cem; Buyukpinarbasili, Nur; Bilir, Ayhan; DENİZ, GÜNNUR

doi:10.5606/tji.2013.268

Interleukin-12 and Protamine Inhibit Angiogenesis and Growth of C6 Rat Glioma: Synergistic Effects and Role of Th2 Cells

TURNA A., KIRAN B., Ozar E., TURNA Z. H., Mercan C. A., Buyukpinarbasili N., ...Daha Fazla

TURKISH JOURNAL OF IMMUNOLOGY, cilt.1, sa.3, ss.68-73, 2013 (ESCI, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 1 Sayı: 3
Basım Tarihi: 2013
Doi Numarası: 10.5606/tji.2013.268
Dergi Adı: TURKISH JOURNAL OF IMMUNOLOGY
Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
Sayfa Sayıları: ss.68-73
Anahtar Kelimeler: Angiogenesis, C6, glioma, interleukin-12, lymphocyte, protamine, Th1 cell, Th2 cell
İstanbul Üniversitesi Adresli: Evet

Özet

Objectives: This study aims to investigate the anti-tumoral, anti-angiogenic and immunologic effects of interleukin-12 (IL-12) in combination with protamine in intracranially inoculated rat C6 glioma model.