A case of fluoxetine-induced syndrome of inappropriate antidiuretic hormone secretion

Ozturk S., Ozsenel E. B., Kazancioglu R., Turkmen A.

Nature Clinical Practice Nephrology, vol.4, no.5, pp.278-282, 2008 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 4 Issue: 5
  • Publication Date: 2008
  • Doi Number: 10.1038/ncpneph0780
  • Journal Name: Nature Clinical Practice Nephrology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.278-282
  • Keywords: fluoxetine, hyponatremia, psychogenic polydipsia, selective serotonin reuptake inhibitor, syndrome of inappropriate antidiuretic hormone secretion, SEROTONIN REUPTAKE INHIBITORS, PSYCHOGENIC POLYDIPSIA, VASOPRESSIN SECRETION, HYPONATREMIA, ANTIDEPRESSANTS, EXCRETION, RISK, RATS
  • Istanbul University Affiliated: Yes

Abstract

Background: A 58-year-old schizophrenic male who had been drinking at least 4-5 l of pure water every day for 30 years was admitted to a hospital with complaints of nausea, fatigue, and irregular, fluctuating fevers (up to 39°C). He had previously been prescribed fluoxetine at a dose of 20 mg/day and had been using the drug for 28 days. Investigations: Review of medical history, physical examination, blood analysis, urine analysis, chest radiography and abdominal ultrasound. Diagnosis: Psychogenic polydipsia and fluoxetine-induced syndrome of inappropriate antidiuretic hormone secretion. Management: Fluid restriction and discontinuation of fluoxetine. ©2008 Nature Publishing Group.