Corrected Panel-Reactive Antibody Positivity Rates for Hypersensitized Patients in Turkish Population With Calculated Panel-Reactive Antibody Software

Creative Commons License

Karadeniz S. T. , Akgul S. U. , Ogret Y., Ciftci H., Bayraktar A., Bakkaloglu H., ...More

TRANSPLANTATION PROCEEDINGS, vol.49, no.3, pp.445-447, 2017 (Peer-Reviewed Journal) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 49 Issue: 3
  • Publication Date: 2017
  • Doi Number: 10.1016/j.transproceed.2017.01.032
  • Journal Indexes: Science Citation Index Expanded, Scopus
  • Page Numbers: pp.445-447


Introduction. High rates of panel-reactive antibody (PRA) may decrease the chance of kidney transplantation and may result in long waiting periods before transplantation. The calculated PRA (cPRA) is performed based on unacceptable HLA antigens. These antigens are identified by a program that was created based on the antibodies that developed against the HLA antigens circulating in serum and on the risk of binding of these antibodies to antigens. The antigen profile of the population and antigen frequencies can be measured, and more realistic cPRA positivity rates may be obtained using this method.