Evaluation of Suspected Macrolide Allergies in Children.

Suleyman A., Yucel E., Tamay Z. U., Guler N.

Turkish archives of pediatrics, vol.57, no.1, pp.81-86, 2022 (ESCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 57 Issue: 1
  • Publication Date: 2022
  • Doi Number: 10.5152/turkarchpediatr.2022.21223
  • Journal Name: Turkish archives of pediatrics
  • Journal Indexes: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Page Numbers: pp.81-86
  • Keywords: Azithromycin, clarithromycin, cross-reaction, drug hypersensitivity, macrolides, DRUG HYPERSENSITIVITY, SKIN-TESTS, DIAGNOSIS, CLARITHROMYCIN, AZITHROMYCIN, SENSITIVITY, CHALLENGE
  • Istanbul University Affiliated: Yes


Objective: Macrolides are often accepted as safe antibiotics due to their low allergenicity. However, studies on macrolides, particularly studies evaluating cross-reactivity in macrolides, are highly rare in children. This study aimed to evaluate the clinical manifestations, confirmation rate, and frequency of cross-reactivity in children admitted with suspicious clarithromycin or azithromycin allergy.