FK506 to prevent lung injury after hindlimb ischemia and reperfusion in a rat model: An electron microscopic study

AKGUN, S; TEKELI, A; ISBIR, SC; CIVELEK, A; AK, K; SIRVANCI, S; ARBAK, S; Yaylim, İlhan; ARSAN, S

doi:10.1007/s00595-004-2799-0

FK506 to prevent lung injury after hindlimb ischemia and reperfusion in a rat model: An electron microscopic study

Copy For Citation

AKGUN S., TEKELI A., ISBIR S., CIVELEK A., AK K., SIRVANCI S., ...More

SURGERY TODAY, vol.34, no.8, pp.678-684, 2004 (SCI-Expanded)

Publication Type: Article / Article
Volume: 34 Issue: 8
Publication Date: 2004
Doi Number: 10.1007/s00595-004-2799-0
Journal Name: SURGERY TODAY
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.678-684
Istanbul University Affiliated: Yes

Abstract

Purpose. Hindlimb ischemia and reperfusion leads to lung injury in various animal models. We investigated the effectiveness of FK506, an immunosuppressive agent, which also modulates neutrophilic infiltration, in preventing lung injury after hindlimb ischemia and reperfusion in a rat model.