Akademik Veri Yönetim Sistemi
Turkiye Klinikleri Cardiovascular Sciences, cilt.22, sa.2, ss.270-272, 2010 (Scopus)
Thrombotic thrombocytopenic purpura (TTP) is a life-threatening multisystemic disease. We present a patient who has been diagnosed with clopidogrel-related TTP. A 53-year-old male patient presented with fever, blurring of consciousness and weakness in right half of his body. Percutaneous transluminal coronary angioplasty and stent implantation had been performed and clopidogrel had been started ten days ago. Before procedure, hemoglobin: 9.9 g/dL, platelet: 155000/μ1, creatinine: 1.1 mg/dL, LDH: 350 U/l. On his admission, hemoglobin: 8.6 g/dL, platelet: 75000/μl, creatinine: 1.7 mg/dL, LDH: 1363 U/l, were detected". Peripheral blood smear showed polychromasia and distinct fragmented erythrocytes. The patient was diagnosed as TTP. Clopidogrel was discontinued. Prednisolone was started as 1 mg/kg/day. But after three days, thrombocytopenia and peripheral blood findings did not improve. Twenty-nine plasmapheresis were performed. The patient was discharged on thirtieth day. Copyright © 2010 by Türkiye Klinikleri.