The importance of sPD-1, sOX40L and sGITR in terms of clinicopathology and histopathology in gastric cancer


Horozoglu C., Sonmez D., Kucukhuseyin O. , Demirkol S., Hakan M. T. , Arikan S., ...More

TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI, vol.46, no.3, pp.273-279, 2021 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 46 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.1515/tjb-2020-0075
  • Title of Journal : TURKISH JOURNAL OF BIOCHEMISTRY-TURK BIYOKIMYA DERGISI
  • Page Numbers: pp.273-279

Abstract

Objectives: Immunoregulatory GITR, OX40L and PD-1 molecules play an active role in the regulation of tumor microenvironment and have been shown in many cancer types. However, there are limited studies of these molecules in terms of gastric cancer. In our study, we aimed to determine the histopathological significance of sPD-1, sOX40L and sGITR levels in gastric cancer cases.