Green synthesis of silver nanoparticles using Schizophyllum commune and Geopora sumneriana extracts and evaluation of their anticancer and antimicrobial activities


Goksen Tosun N., Kaplan O., TÜRKEKUL İ., GÖKÇE İ., Ozgur A.

PARTICULATE SCIENCE AND TECHNOLOGY, vol.40, no.7, pp.801-811, 2022 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 40 Issue: 7
  • Publication Date: 2022
  • Doi Number: 10.1080/02726351.2021.2010846
  • Journal Name: PARTICULATE SCIENCE AND TECHNOLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Applied Science & Technology Source, Aquatic Science & Fisheries Abstracts (ASFA), Chemical Abstracts Core, Communication Abstracts, Compendex, Computer & Applied Sciences, EMBASE, INSPEC, Metadex, Pollution Abstracts, Civil Engineering Abstracts
  • Page Numbers: pp.801-811
  • Keywords: Silver nanoparticles, green synthesis, mushroom, cancer, infection, ANTIBACTERIAL
  • Istanbul University Affiliated: Yes

Abstract

Silver nanoparticles (AgNPs) have big potentials in designing next-generation anticancer and antimicrobial agents. Here, AgNPs were synthesized with green chemistry using edible mushrooms Schizophyllum commune and Geopora sumneriana. The synthesized AgNPs were characterized with ultraviolet-visible spectrophotometry (UV-Vis), Fourier transform infrared spectrophotometer (FTIR), scanning transmission electron microscope (S-TEM), energy dispersive spectrometry (EDS), x-ray diffraction (XRD), and dynamic light scattering (DLS) techniques. Anticancer activities of the synthesized S. commune (SC-AgNPs) and G. sumneriana (GS-AgNPs) were studied on the breast (MCF-7), lung (A549), colon (HT-29), and liver (HUH-7) cancer cell lines. Also, the antimicrobial potential of SC-AgNPs and GS-AgNPs was determined against pathogens bacteria (Pseudomonas aeruginosa, Klebsiella pneumonia, Staphylococcus aureus, and Enterococcus faecalis) and fungal (Candida albicans and Candida utilis) strains. Obtained results demonstrated that the synthesized SC-AgNPs and GS-AgNPs have anticancer and antimicrobial activity. Our study implicates that SC-AgNPs and GS-AgNPs have great potentials for the treatment of cancer and infectious diseases.