Effects of sodium hyaluronate and methylprednisolone alone or in combination in preventing epidural fibrosis.


Shaban M., Aras Y. , Aydoseli A. , Akcakaya M. O. , Sencer A. , Bayindir C., ...More

Neurological research, vol.35, no.8, pp.851-6, 2013 (Journal Indexed in SCI Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 8
  • Publication Date: 2013
  • Doi Number: 10.1179/1743132813y.0000000219
  • Title of Journal : Neurological research
  • Page Numbers: pp.851-6

Abstract

Objective: Epidural fibrosis and leptomeningeal adhesion formation are common causes of failed back surgery syndrome (FBSS). We employed a rat model of lumbar laminectomy to evaluate the histopathological effects of sodium hyaluronate (HA) and methylprednisolone (MP) alone or in combination on post-laminectomy epidural fibrosis.