The Effects of Nitric Oxide and Inhibitor, and Combination of Albendazole and Praziquantel On Liver in Mice Injected with Echinococcus granulosus Larvae.

Kandil A., Keles A. G., Balci H., Demirci-Tansel C.

Acta tropica, vol.219, pp.105917, 2021 (SCI-Expanded) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 219
  • Publication Date: 2021
  • Doi Number: 10.1016/j.actatropica.2021.105917
  • Journal Name: Acta tropica
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Aerospace Database, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, CAB Abstracts, Communication Abstracts, EMBASE, Geobase, MEDLINE, Metadex, Veterinary Science Database, Civil Engineering Abstracts
  • Page Numbers: pp.105917
  • Keywords: Echinococcus granulosus, hydatidosis, liver, nitric oxide, anthelmintic drugs, IN-VITRO, PHARMACOKINETIC INTERACTION, LIPID-PEROXIDATION, HUMAN HYDATIDOSIS, IFN-GAMMA, TNF-ALPHA, CYSTS, NO, EXPRESSION, SULFOXIDE
  • Istanbul University Affiliated: Yes


In this study, the role of nitric oxide (NO) in the pathogenesis of hydatidosis and the interaction with effects of anthelmintic drugs, albendazole and praziquantel, were examined in larval infection caused by protoscolices obtained from hydatid cysts of sheep liver in Albino Balb/c mice.