Teratogenicity of Antiepileptic Drugs.

Guveli, Betul; Rosti, Rasim; Guzeltas, Alper; Tuna, Elif; Atakli, Dilek; Sencer, Nebiye; Yekeler, Ensar; Kayserili, Hulya; Dirican, Ahmet; Bebek, Nerses; Baykan, Betül; Gokyigit, Aysen; Gurses, Rabia

doi:10.9758/cpn.2017.15.1.19

Teratogenicity of Antiepileptic Drugs.

Guveli B. T., Rosti R. O., Guzeltas A., Tuna E. B., Atakli D., Sencer S., ...More

Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology, vol.15, no.1, pp.19-27, 2017 (SCI-Expanded)

Publication Type: Article / Article
Volume: 15 Issue: 1
Publication Date: 2017
Doi Number: 10.9758/cpn.2017.15.1.19
Journal Name: Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.19-27
Keywords: Dysmorphic features, Dental anomalies, Congenital malformations, Antiepileptic drugs, Teratogenesis, TECHNOLOGY-ASSESSMENT SUBCOMMITTEE, QUALITY STANDARDS SUBCOMMITTEE, AMERICAN EPILEPSY SOCIETY, UPDATE MANAGEMENT ISSUES, CONGENITAL-MALFORMATIONS, IN-UTERO, CHILDREN BORN, FOLIC-ACID, PREGNANCY, WOMEN
Istanbul University Affiliated: Yes

Abstract

Objective: Antiepileptic drugs (AED) have chronic teratogenic effects, the most common of which are congenital heart disease, cleft lip/palate, urogenital and neural tube defects. The aim of our study is to examine teratogenic effects of AED and the correlation between these malformations and AED in single or multiple pregnancies.