Effect of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier permeability and brain edema after experimental traumatic diffuse brain injury

Imer, Murat; Omay, Bulent; Uzunkol, Ajlan; Erdem, Tulin; Sabanci, Pulat; Karasu, Aykut; Albayrak, Serdar; Sencer, Altay; Hepgul, Kemal; Kaya, Mehmet

doi:10.1179/174313209x385617

Effect of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier permeability and brain edema after experimental traumatic diffuse brain injury

Imer M., Omay B., Uzunkol A., Erdem T., Sabanci P. A. , Karasu A. , ...More

NEUROLOGICAL RESEARCH, vol.31, no.9, pp.977-981, 2009 (Journal Indexed in SCI)

Publication Type: Article / Article
Volume: 31 Issue: 9
Publication Date: 2009
Doi Number: 10.1179/174313209x385617
Title of Journal : NEUROLOGICAL RESEARCH
Page Numbers: pp.977-981

Abstract

Objective: Glutamate antagonists are very attractive drugs in laboratory works to protect neural tissue against ischemia. In this work, the effects of magnesium, MK-801 and combination of magnesium and MK-801 on blood-brain barrier (BBB) and brain edema after experimentally induced traumatic brain injury are evaluated.