Remembering the Basics: A Patient with Sickle Cell Disease and Proteinuria

Ozbalak E. P., Mirioglu S., Sahin E., Ozluk Y., Ucar A. R., Yazici H., ...More

TURKISH JOURNAL OF NEPHROLOGY, vol.28, no.2, pp.154-156, 2019 (ESCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 28 Issue: 2
  • Publication Date: 2019
  • Doi Number: 10.5152/turkjnephrol.2019.3198
  • Journal Indexes: Emerging Sources Citation Index (ESCI), Scopus, TR DİZİN (ULAKBİM)
  • Page Numbers: pp.154-156
  • Istanbul University Affiliated: Yes


Patients with sickle cell disease (SCD) tend to develop many renal abnormalities, including concentration defect, renal papillary necrosis, and glomerulopathy that often presents with proteinuria. We report a case of a patient who presented with sickle cell crisis and proteinuria. A diagnosis of SCD glomerulopathy was confirmed with renal biopsy. Treatment with angiotensin-converting enzyme inhibitor was initiated, and proteinuria rapidly reduced to 0.27 g/day. It is crucial for a clinician to recognize this important complication and take necessary precautions to delay progression to end-stage renal disease.