Vascular endothelial growth factor polymorphisms increase the risk of developing Graves' disease

Vural P., Baki M., Dogru-Abbasoglu S., OZDERYA A., KARADAG B., Uysal M.

INTERNATIONAL IMMUNOPHARMACOLOGY, cilt.14, sa.2, ss.133-137, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1016/j.intimp.2012.06.018
  • Dergi Adı: INTERNATIONAL IMMUNOPHARMACOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.133-137
  • İstanbul Üniversitesi Adresli: Evet

Özet

Background: Graves' disease (GD) is a consequence of genetic and environmental factors. Vascular endothelial growth factor (VEGF) is a strong angiogenic and mitogenic factor, which plays a key role in lymphocyte infiltration, and hypervascularization in the thyroid gland of patients with GD.