Tumor necrosis factor alpha (-308), interleukin-6 (-174) and interleukin-10 (-1082) gene polymorphisms in polycystic ovary syndrome

Vural, Pervin; Degirmencioglu, Sevgin; Saral, Nihan; Akgul, Cemil

doi:10.1016/j.ejogrb.2010.02.010

Tumor necrosis factor alpha (-308), interleukin-6 (-174) and interleukin-10 (-1082) gene polymorphisms in polycystic ovary syndrome

Atıf İçin Kopyala

Vural P., Degirmencioglu S., Saral N., Akgul C.

EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY, cilt.150, sa.1, ss.61-65, 2010 (SCI-Expanded)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 150 Sayı: 1
Basım Tarihi: 2010
Doi Numarası: 10.1016/j.ejogrb.2010.02.010
Dergi Adı: EUROPEAN JOURNAL OF OBSTETRICS & GYNECOLOGY AND REPRODUCTIVE BIOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.61-65
İstanbul Üniversitesi Adresli: Evet

Özet

Objective: The imbalance between pro- and anti-inflammatory cytokines and polymorphism of cytokine genes may play a role in the etiology of the polycystic ovary syndrome (PCOS). The aim of this study was to investigate the association of polymorphisms of TNF alpha. IL-6 and IL-10 genes with the occurrence and the clinical/laboratory characteristics of PCOS in the Turkish population.