Influence of Interferon alpha-2a Treatment on Monocyte Subsets in Patients with Uveitis

Esen F., Türkyilmaz Ö., Aykut V., Direskeneli H., Deniz G., Oğuz H., ...Daha Fazla

TURKISH JOURNAL OF IMMUNOLOGY, cilt.8, sa.2, ss.50-56, 2020 (ESCI) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 8 Sayı: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.25002/tji.2020.1261
  • Dergi Adı: TURKISH JOURNAL OF IMMUNOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, Academic Search Premier, EMBASE, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.50-56
  • Anahtar Kelimeler: Monocyte, Behcet's disease, uveitis, interferon alpha, PD-1, ADALIMUMAB, ACTIVATION, EFFICACY, THERAPY, SAFETY, CELLS
  • İstanbul Üniversitesi Adresli: Evet

Özet

Introduction: Interferon alpha is a type-I interferon molecule with antiviral and antineoplastic properties. Interferon a treatment is also used in the management of uveitis and believed to have immunomodulatory properties demonstrated by increased number of regulatory T cells. The aim of this study was to define the influence of interferon alpha-2a treatment on monocyte subsets in patients with uveitis.