Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammation

Aksu, Uğur; BEZEMER, Rick; Yavuz, Berna; Kandil, Aslı; Demirci, Cihan; İNCE, Can

doi:10.1016/j.resuscitation.2011.11.022

Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammation

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Aksu U., BEZEMER R., Yavuz B., Kandil A., Demirci C., İNCE C.

RESUSCITATION, vol.83, no.6, pp.767-773, 2012 (SCI-Expanded)

Publication Type: Article / Article
Volume: 83 Issue: 6
Publication Date: 2012
Doi Number: 10.1016/j.resuscitation.2011.11.022
Journal Name: RESUSCITATION
Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Page Numbers: pp.767-773
Keywords: Fluid resuscitation, Hemorrhagic shock, Oxygen, Reactive oxygen species, Glycocalyx, Inflammation, Kidney, NITRIC-OXIDE PRODUCTION, HYPERCHLOREMIC ACIDOSIS, METABOLIC-ACIDOSIS, CONSUMPTION, INFUSION, SALINE, GLYCOCALYX, EXPRESSION, LEUKOCYTES, ETIOLOGY
Istanbul University Affiliated: Yes

Abstract

Background: The aim of the present study was to test the hypothesis that balanced crystalloid resuscitation would be better for the kidney than unbalanced crystalloid resuscitation in a rat hemorrhagic shock model.