SERUM AKT2 LEVELS AS A MARKER FOR LUNG CANCER

Karaman S., Erturk K., Serilmez M., Duranyilidiz D., Oral E. N., Dagoglu N.

ACTA MEDICA MEDITERRANEA, vol.35, no.6, pp.3269-3272, 2019 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 35 Issue: 6
  • Publication Date: 2019
  • Doi Number: 10.19193/0393-6384_2019_6_514
  • Journal Name: ACTA MEDICA MEDITERRANEA
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.3269-3272
  • Istanbul University Affiliated: Yes

Abstract

Introduction: AKT overexpression has shown in some cancer types such as breast, prostate, ovarian and gastric cancer (1, 2, 3). Due to conflicting results reported in recent studies investigating the phosphoinositide-3-kinase-protein kinase (PI3K) signal transduction pathway and lung cancer, we know AKT2 plays a critical role (4). The aim of our study is to investigate whether circulating AKT2 levels have diagnostic, predictive and prognostic role in lung cancer.