RESUSCITATION, vol.83, no.9, pp.1166-1172, 2012 (SCI-Expanded)
Article / Article
Science Citation Index Expanded (SCI-EXPANDED), Scopus
Colloid, Crystalloid, Resuscitation, Renal oxygenation, Hemorrhagic shock, Microcirculation, MAJOR ABDOMINAL-SURGERY, LACTATED RINGERS SOLUTION, FLUID RESUSCITATION, HYPERCHLOREMIC ACIDOSIS, METABOLIC-ACIDOSIS, ENDOTHELIAL ACTIVATION, TRANSFUSION TRIGGER, EXPERIMENTAL SEPSIS, HYPERTONIC SALINE, CRITICALLY-ILL
Istanbul University Affiliated:
Introduction: Fluid resuscitation therapy is the initial step of treatment for hemorrhagic shock. In the present study we aimed to investigate the acute effects of acetate-balanced colloid and crystalloid resuscitation on renal oxygenation in a rat model of hemorrhagic shock. We hypothesized that acetate-balanced solutions would be superior in correcting impaired renal perfusion and oxygenation after severe hemorrhage compared to unbalanced solutions.