A RARE CASE OF MUCINOUS CARCINOMA OF THE BREAST IN A 30-YEAR-OLD FEMALE


Emiroğlu S., Abuaisha A., Tükenmez M., Kaya M., Suer İ., Bayram A., ...More

4th International Congress on Medical Sciences and Multidisciplinary Approaches, 26 March - 28 August 2022, pp.895

  • Publication Type: Conference Paper / Summary Text
  • Page Numbers: pp.895
  • Istanbul University Affiliated: Yes

Abstract

Mucinous carcinoma is a rare type of cancer that can arise in any epithelial tissue where mucus is produced. Mucinous carcinoma of the breast (MCB) or colloid carcinoma is a rare histological subtype of infiltrating ductal carcinoma that makes up about 1-7% of all invasive breast cancer (BC) types. MCB is typically distinguished by the presence of a large amount of extracellular mucin. Based on the mucin contents, there are two main subtypes of MCB; Pure Mucinous Carcinoma of the breast (PMCB) and Mixed Mucinous Carcinoma of the breast (MMCB). Generally, MCB has estrogen receptors (ER) and progesterone receptors (PR) positive and HER2 negative. Here, we report a case of PMCB nuclear grade 2 in a 30-year-old female. The patient applied to our department with a complaint of palpable mass in her left breast for 12 months. In the physical examination, we suspected the presence of breast carcinoma. Thus, further radiological and pathological investigations were requested. As a result of the pathological investigations, we found that this patient is a PMCB nuclear grade 2 with ER and PR 90% positive, HER2 negative and Ki67 10% positive (T3N0M0). According to our multidisciplinary meeting, nipple sparing mastectomy and sentinel lymph node biopsy as well as hormone replacement therapy and radiotherapy were used to treat the patient. Considering that the incidence of MCB is only 1% in women under the age of 35, we believe that sharing our case will raise awareness about MCB which is rarely seen at a young age.