Hemodiafiltration Is Associated With Reduced Inflammation and Increased Bone Formation Compared With Conventional Hemodialysis in Children: The HDF, Hearts and Heights (3H) Study


Fischer D., Smith C., De Zan F., Bacchetta J., BAKKALOĞLU EZGÜ S. A. , AĞBAŞ A., ...More

KIDNEY INTERNATIONAL REPORTS, vol.6, no.9, pp.2358-2370, 2021 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 6 Issue: 9
  • Publication Date: 2021
  • Doi Number: 10.1016/j.ekir.2021.06.025
  • Journal Name: KIDNEY INTERNATIONAL REPORTS
  • Journal Indexes: Science Citation Index Expanded, Scopus, EMBASE, Directory of Open Access Journals
  • Page Numbers: pp.2358-2370
  • Keywords: hemodiafiltration, hemodialysis, inflammation, mineral bone disease, pediatric nephrology, CHRONIC KIDNEY-DISEASE, GROWTH-FACTOR 23, LEFT-VENTRICULAR HYPERTROPHY, TNF-ALPHA, ONLINE HEMODIAFILTRATION, CLINICAL-PRACTICE, VASCULAR CALCIFICATION, SYSTEMIC INFLAMMATION, ALKALINE-PHOSPHATASE, BIOCHEMICAL MARKERS

Abstract

Background: Patients on dialysis have a high burden of bone-related comorbidities, including fractures. We report a post hoc analysis of the prospective cohort study HDF, Hearts and Heights (3H) to determine the prevalence and risk factors for chronic kidney disease-related bone disease in children on hemodiafiltration (HDF) and conventional hemodialysis (HD).